Postdoctoral researcher

My journey in plant sciences integrates plant adaptation to environmental stress, redox mechanisms, and epigenetics. Trained at the University of Perpignan Via Domitia and the University of Toulouse Paul Sabatier in France, I developed expertise in molecular biology and genetics, laying the foundation for my research career. In October 2019, I commenced my PhD under Dr. Jean-Philippe Reichheld's supervision at the Laboratory of Plant's Genome and Development in Perpignan, France. Our research revealed redox mechanisms' significance in plant adaptation to heat waves and their impact on chromatin regulators, including histone deacetylases HDA6 and HDA19. After defending my thesis successfully in May 2023, I began my first postdoc in Prof. Dr. Frank Van Breusegem's lab at VIB-Ugent Center for Plant System Biology in Ghent, Belgium. My initial project focused on uncovering redox-sensitive proteins in the nucleus using redox proteomics. In April 2024, I secured the prestigious MSCA postdoc fellowship to initiate my independent research within the same team. This project involves developing new tools like genetically encoded redox proteomics probes and biosensors to investigate the role of redox regulation in stress granule formation during heat stress.

Mingjian Zhou obtained his bachelor degree in bioengineering at Jiangsu University of Science and Technology in China. He begins a continuous academic project that involves postgraduate and doctoral study on Biochemistry and Molecular Biology at Nanjing agricultural University from September 2020. He focused on the redox-based regulation of hydrogen sulfide and persulfidation and mechanisms of osmotic and drought tolerance in plants. He joined oxidative stress signaling research group of Professor Frank since November 2022 as a joined Ph.D. student and based the topic of “Thiol-Based Protection Mechanisms In Plant Stress Responses: From S-Sulfenylation To Persulfidation”.

Carmen Castell obtained her Biology Degree at the University of Seville, where she joined the lab of Dr. Navarro and Prof. Hervás at the Institute of Plant Biochemistry and Photosynthesis (CSIC-US). Subsequently, she obtained a Collaboration Scholarship from the Spanish Government and conducted her Master´s degree in Molecular Genetics and Biotechnology at the University of Seville. With various competitive national scholarships, she completed her PhD thesis focusing on the improvement of productivity of the diatom Phaeodactylum tricornutum under stress conditions by using different biotechnological approaches. Currently, she has joined Prof. Van Breusegem´s group (Oxidative Stress Signaling group) as a postdoctoral researcher. 

Jingjing Huang obtained the master degree in Molecular biology and Biochemistry from Nanjing Agricultural University (China) in 2009. In 2010, She Joined the Delledonne lab in the University of Verona (Italy) to study the origins of nitric oxide in plants and mechanism that how plants perceive and transduce the nitric oxide signal in cellular pathways. She obtained the PhD degree in Biotechnology in 2014. From June 2014 till October 2016, she worked in the Messens lab in VIB-VUB center for Structural Biology, mainly focused on focued on in vitro biochemical study on the S-sulfenylated plant proteins. Since November 2016, she continued her research work on Cys OxiPTM to work in the Van Breusegem in VIB-UGent center for Plant System Biology. From September to December in 2018, Jingjing has worked in Claire Remacle lab in the University of Liege on project "Organellar Redox Signaling in Plants". Since October 2019, Jingjing works as a senior FWO postdoctoral fellow in the Van Breusegem lab focusing on Cysteine oxidations in plants.

PhD fellow

Simon Tack obtained his Bachelors in Biochemistry and Biotechnology at the University of Ghent (UGhent, Belgium). He stayed at UGhent to persue a Master in Molecular Plant Biology. During his Master-thesis he joined the VIB-UGhent 'Oxidative Stress Signaling' lab (led by Prof. Dr. F. Van Breusegem) where he focused on showing Metacaspase activity using FRET-based sensors under the guidance of Dr. A.D. Fernandez Fernandez and Prof. Dr. S. Stael. In November 2022 he joined the OSS lab as a PhD fellow and continues his efforts on showing protease activity in plants (Arabidopsis thaliana and Brassica napus) under the direct supervision of Prof. Dr. Van Breusegem.

Frank Van Breusegem obtained his Bachelor and Master degree at Ghent University. He is a group leader of the Oxidative Stress Signaling group at the VIB Center for Plant Systems Biology (since 2001); full professor at Ghent University and he recently was elected vice-chair of the Department of Plant Biotechnology and Bioinformatics (Faculty of Sciences, Ghent University). Since his early studies under the supervision of em. Prof. Marc Van Montagu, he focuses on the molecular impact of oxidative stress on plant cells. He obtained his PhD from Ghent University (1997) with work on “Engineering Stress Tolerance in Maize”. Nowadays, the primary objective of the Van Breusegem lab is the identification and functional analysis of regulatory gene and protein networks involved in the oxidative stress response in plants. Ultimately, he aims to translate this knowledge into biotechnological crop efficiency concepts. The lab has played a pioneering role in determining H₂O₂-dependent molecular and physiological responses in plants. The Van Breusegem lab is internationally recognized mainly because of its successful multi-omics driven approaches that allowed to identify several key targets in the oxidative stress response. Frank Van Breusegem has published more than 150 peer-reviewed publications (Clarivate h-index=59), is a frequent invited speaker and is monitoring editor of the leading plant journal “Plant Physiology”.

Jawad has obtained his Master degree in Biotechnology from National Institute for Biotechnology and Genetic Engineering (NIBGE) PIEAS, Pakistan. He did his masters thesis at Microbial Ecology Lab under the supervision of Dr. Asma Imran, where he studied the molecular and genetic mechanisms of drought tolerance in bacteria to utilize their plant beneficial traits during plant-microbe interaction. In July 2022, he started his PhD research in the Oxidative Stress Signaling group of Prof. Dr. Frank Van Breusegem in the VIB-UGent Center for Plant System Biology. He is studying oxidative post-translational cysteine modifications using protein-based thiol traps.

Jonas De Backer graduated in 2019 as Master of Bioscience Engineering: Cell and Gene Biotechnology (Bio-engineer) at the faculty of Bioscience Engineering at Ghent University. During his master thesis under the guidance of Prof. Monica Höfte and Dr. Inge De Clercq at the Oxidative Stress Signaling group of Prof. Van Breusegem, he was involved in the study of the post-translational activation of transcription factors involved in retrograde signaling of plant stress responses. On the 1st of January 2020, he started his PhD in the EOS project Retrograde Arabidopsis Chlamydomonas Thiol signaling (ReACTs) to further study this topic while applying for an FWO predoctoral fellowship for fundamental research which he obtained that same year. Now he is doing his joint PhD entitled “Identification of proteases that activate membrane-bound transcription factors during mitochondrial retrograde regulation“ in the inter-organellar signaling lab of Prof. De Clercq in collaboration with the lab of Prof. Monica Höfte (Lab of Phytopathology, Ghent University) and the lab of Prof. Frank Van Breusegem (Lab of Oxidative Stress Signaling, PSB VIB-UGent).