Postdoctoral researcher

My journey in plant sciences integrates plant adaptation to environmental stress, redox mechanisms, and epigenetics. Trained at the University of Perpignan Via Domitia and the University of Toulouse Paul Sabatier in France, I developed expertise in molecular biology and genetics, laying the foundation for my research career. In October 2019, I commenced my PhD under Dr. Jean-Philippe Reichheld's supervision at the Laboratory of Plant's Genome and Development in Perpignan, France. Our research revealed redox mechanisms' significance in plant adaptation to heat waves and their impact on chromatin regulators, including histone deacetylases HDA6 and HDA19. After defending my thesis successfully in May 2023, I began my first postdoc in Prof. Dr. Frank Van Breusegem's lab at VIB-Ugent Center for Plant System Biology in Ghent, Belgium. My initial project focused on uncovering redox-sensitive proteins in the nucleus using redox proteomics. In April 2024, I secured the prestigious MSCA postdoc fellowship to initiate my independent research within the same team. This project involves developing new tools like genetically encoded redox proteomics probes and biosensors to investigate the role of redox regulation in stress granule formation during heat stress.

Mingjian Zhou obtained his bachelor degree in bioengineering at Jiangsu University of Science and Technology in China. He begins a continuous academic project that involves postgraduate and doctoral study on Biochemistry and Molecular Biology at Nanjing agricultural University from September 2020. He focused on the redox-based regulation of hydrogen sulfide and persulfidation and mechanisms of osmotic and drought tolerance in plants. He joined oxidative stress signaling research group of Professor Frank since November 2022 as a joined Ph.D. student and based the topic of “Thiol-Based Protection Mechanisms In Plant Stress Responses: From S-Sulfenylation To Persulfidation”.

Jingjing Huang obtained the master degree in Molecular biology and Biochemistry from Nanjing Agricultural University (China) in 2009. In 2010, She Joined the Delledonne lab in the University of Verona (Italy) to study the origins of nitric oxide in plants and mechanism that how plants perceive and transduce the nitric oxide signal in cellular pathways. She obtained the PhD degree in Biotechnology in 2014. From June 2014 till October 2016, she worked in the Messens lab in VIB-VUB center for Structural Biology, mainly focused on focued on in vitro biochemical study on the S-sulfenylated plant proteins. Since November 2016, she continued her research work on Cys OxiPTM to work in the Van Breusegem in VIB-UGent center for Plant System Biology. From September to December in 2018, Jingjing has worked in Claire Remacle lab in the University of Liege on project "Organellar Redox Signaling in Plants". Since October 2019, Jingjing works as a senior FWO postdoctoral fellow in the Van Breusegem lab focusing on Cysteine oxidations in plants.

PhD fellow

Simon Tack obtained his Bachelors in Biochemistry and Biotechnology at the University of Ghent (UGhent, Belgium). He stayed at UGhent to persue a Master in Molecular Plant Biology. During his Master-thesis he joined the VIB-UGhent 'Oxidative Stress Signaling' lab (led by Prof. Dr. F. Van Breusegem) where he focused on showing Metacaspase activity using FRET-based sensors under the guidance of Dr. A.D. Fernandez Fernandez and Prof. Dr. S. Stael. In November 2022 he joined the OSS lab as a PhD fellow and continues his efforts on showing protease activity in plants (Arabidopsis thaliana and Brassica napus) under the direct supervision of Prof. Dr. Van Breusegem.

Frank Van Breusegem obtained his Bachelor and Master degree at Ghent University. He is a group leader of the Oxidative Stress Signaling group at the VIB Center for Plant Systems Biology (since 2001); full professor at Ghent University and he recently was elected vice-chair of the Department of Plant Biotechnology and Bioinformatics (Faculty of Sciences, Ghent University). Since his early studies under the supervision of em. Prof. Marc Van Montagu, he focuses on the molecular impact of oxidative stress on plant cells. He obtained his PhD from Ghent University (1997) with work on “Engineering Stress Tolerance in Maize”. Nowadays, the primary objective of the Van Breusegem lab is the identification and functional analysis of regulatory gene and protein networks involved in the oxidative stress response in plants. Ultimately, he aims to translate this knowledge into biotechnological crop efficiency concepts. The lab has played a pioneering role in determining H₂O₂-dependent molecular and physiological responses in plants. The Van Breusegem lab is internationally recognized mainly because of its successful multi-omics driven approaches that allowed to identify several key targets in the oxidative stress response. Frank Van Breusegem has published more than 150 peer-reviewed publications (Clarivate h-index=59), is a frequent invited speaker and is monitoring editor of the leading plant journal “Plant Physiology”.

Jawad has obtained his Master degree in Biotechnology from National Institute for Biotechnology and Genetic Engineering (NIBGE) PIEAS, Pakistan. He did his masters thesis at Microbial Ecology Lab under the supervision of Dr. Asma Imran, where he studied the molecular and genetic mechanisms of drought tolerance in bacteria to utilize their plant beneficial traits during plant-microbe interaction. In July 2022, he started his PhD research in the Oxidative Stress Signaling group of Prof. Dr. Frank Van Breusegem in the VIB-UGent Center for Plant System Biology. He is studying oxidative post-translational cysteine modifications using protein-based thiol traps.

Mathias Cohen - Predoctoral fellow

Mathias Cohen graduated in 2012 as Expert in Biotechnology Engineering from Sup’Biotech, Villejuif (France). Then he obtained a Master in Biology, with a specialization in molecular and cellular biology, at the University of Sherbrooke (Canada) in 2017. During this research master, he worked in the group of Peter Moffett, that focuses on the study of the plant innate immune system. He studied the translational control of Arabidopsis thaliana genes in the specific context of the Effector-Triggered Immunity, as well as the molecular mechanisms governing processing bodies formation during plant-virus interactions. In 2018, he started to work as an engineer in the lab of Isabelle Jupin, in the Institut Jacques Monod, Paris (France). His work concerned the study of plant-pathogen interactions between Arabidopsis thaliana and the Turnip Yellow Mosaic Virus. In October 2020, he started a joint PhD between the CCARS group of Pr. Graham Noctor (Climate Change and Redox Signaling, IPS2, Universite Paris-Saclay, France) and the OSS group of Pr. Frank Van Breusegem (Oxidative Stress Signaling, PSB, VIB-UGent, Belgium). The topic of his PhD is the elucidation of the mechanisms in play in the activation of the salicylic acid pathway by environmental and redox factors in Arabidopsis thaliana.